Yes & No! However it is important to realize that PunctureSafe cannot hide or mask a dangerous puncture. Sidewalls are much thinner than the rest of the tire, so even though there is some rubber recovery, because of the flexing, the tire will lose air to some degree. If there is no damage, then it could be possible to seal permanently. It could also be the case that even with severe damage to the sidewall, a controlled deflation will take place allowing the driver to remove the vehicle from a dangerous location.